Cleanser and Moisturizer for Regimen of Atopic Dermatitis

Eczema refers to a skin condition that causes inflammation, swelling, irritation, and itching. One of eczema common type is atopic dermatitis. As happened with other atopic, such as asthma and allergic rhinitis (hay fever), atopic dermatitis is related with genetic problem, therefore the skin barrier becomes abnormal.

In fact, 85% atopic dermatitis patients have onset before the age of 5 years. In addition to the children, eczema can also occur in adults. The symptoms of Eczema are vary and not the same for every individual. But the most common is itching. The itching causes children to scratch to eliminate it. Unfortunately, scratching can actually aggravate the skin condition. The trigger can be an irritant such as soap and detergents, skin infections, contact will allergens, food allergies, and inhalant. Staphylococcus aureus is known as one of microbe types that can cause atopic dermatitis.

“Itching is humane, but scratching it is a different thing,” said Donne Marie Leelin-Sarrosa, MD, FPDS, from Philippines, in Galderma Scientific Night at Ritz Carlton Hotel, Jakarta, Februari 27th 2015. The get-together night was a part of Kelompok Studi Dermatologi Kosmetik Indonesia (KSDKI) event, started from February 27th to March 1st 2015.

According to Fellow in Dermatology (FDS), with subspecialty Pediatric Dermatology and Laser Surgery, the itch can be treated by topical steroid/TCI for itchy inflammation, antihistamines, and antidepressants with doxepin (soporific). Unfortunately, antihistamines have several side effects, like the effect of sleeping pills, sleep disorders due to itching, dermatographysme allergic, as well as allergic rhinoconjunctivitis.

The report from Cochrane Database System Rev 2013 has found no evidence of the efficacy and safety of using oral antihistamines. Meanwhile, using the antibacterial soaps have not been enough to prevent microbes. Other treatment that can be done is a bleach bath that effectively reduces S. aureus and using topical corticosteroids (TCS). However, it should be remembered to measure the bleach carefully. In addition, the tongue blade/clean spoon should also be used to prevent contamination. Meanwhile, the use of TCS should be accompanied by education for patients, such as TCS is not a moisturizer.

The strategy of atopic dermatitis treatment can be done by bathing and moisturizing. “The strategy is done by eliminating some bacteria from the skin, doing exfoliation, doing hydration, and applying moisturizer after bathing,” said Donna Marie.

Moisturizers can improve the skin barrier by restoring skin lipids. Clinically, moisturizers can also increase the water content in the stratum corneum, sooth the skin surface, restore the skin mechanism, and enhance the skin barrier function. Using the skin restoring body wash and skin restoring moisturizer is known to improve the barrier by reducing Transepidermal Water Loss and also able to enhance the skin hydration. Cleaning agents and moisturizers are well tolerated with high satisfaction rates among infants and children.

The ideal moisturizer should be safe. It means without percutaneous absorption, toxin-free, durable, well tolerated, and no side effects such as irritation, allergy, and folliculitis. According to Journal of Drugs and Dermatology 2013, the treatment for atopic dermatitis is focused on using specific cleanser and moisturizer that combine Ceramide precursor, Filaggrin Degradation Products, and friendly excipient to the skin barrier. The ingredients in the specific cleanser and moisturizer are Pseudo Ceramide 5, Sunflower seed oil, Shea butter, Filaggrin, Niacinamide, and Glycerin. Meanwhile, the moisturizer types are topical moisturizer, emollients, humectants, and occlusion.

The standard moisturizer and cleanser for atopic dermatitis regimen, which should be safe and easy to apply, are presented by Galderma Production Canada Inc. with Cetaphil® Restoraderm as the brand name. The products are Skin Restoring Body Moisturizer with Filaggrin & Ceramide precursors, and Skin Restoring Body Wash with Filaggrin & Miracare® technology. Both products have the ability to restore and maintain the integrity and barrier function of the skin. In addition, this product is also effective to sooth dry and itchy skin, while improving the life quality of patients. Use these two products simultaneously in the daily care of atopic dermatitis for optimal results. This product is safe for all atopic dermatitis patients, including a 3-month baby, toddlers, and children.

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